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1.
Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition.
Proc Natl Acad Sci U S A;
120(19): e2221045120, 2023 05 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37126699
2.
Chemiexcitation and melanin in photoreceptor disc turnover and prevention of macular degeneration.
Proc Natl Acad Sci U S A;
120(20): e2216935120, 2023 05 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-37155898
3.
Interleukin-17-mediated protective cytokine signaling against degeneration of the retinal pigment epithelium.
Proc Natl Acad Sci U S A;
120(51): e2311647120, 2023 Dec 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38085785
4.
Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration.
Hum Mol Genet;
32(2): 204-217, 2023 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35943778
5.
Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.
EMBO J;
40(6): e105123, 2021 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33555074
6.
NURR1 expression regulates retinal pigment epithelial-mesenchymal transition and age-related macular degeneration phenotypes.
Proc Natl Acad Sci U S A;
119(28): e2202256119, 2022 07 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-35867766
7.
Mast cell infiltration of the choroid and protease release are early events in age-related macular degeneration associated with genetic risk at both chromosomes 1q32 and 10q26.
Proc Natl Acad Sci U S A;
119(20): e2118510119, 2022 05 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-35561216
8.
Crosstalk of protein clearance, inflammasome, and Ca2+ channels in retinal pigment epithelium derived from age-related macular degeneration patients.
J Biol Chem;
299(6): 104770, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37137441
9.
Functional analysis of rare genetic variants in complement factor I in advanced age-related macular degeneration.
Hum Mol Genet;
31(21): 3683-3693, 2022 10 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35531992
10.
TNFRSF10A downregulation induces retinal pigment epithelium degeneration during the pathogenesis of age-related macular degeneration and central serous chorioretinopathy.
Hum Mol Genet;
31(13): 2194-2206, 2022 07 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35103281
11.
Common haplotypes at the CFH locus and low-frequency variants in CFHR2 and CFHR5 associate with systemic FHR concentrations and age-related macular degeneration.
Am J Hum Genet;
108(8): 1367-1384, 2021 08 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34260947
12.
Beyond factor H: The impact of genetic-risk variants for age-related macular degeneration on circulating factor-H-like 1 and factor-H-related protein concentrations.
Am J Hum Genet;
108(8): 1385-1400, 2021 08 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34260948
13.
Impaired cholesterol efflux in retinal pigment epithelium of individuals with juvenile macular degeneration.
Am J Hum Genet;
108(5): 903-918, 2021 05 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33909993
14.
Transcriptomic and Chromatin Accessibility Analysis of the Human Macular and Peripheral Retinal Pigment Epithelium at the Single-Cell Level.
Am J Pathol;
193(11): 1750-1761, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-36775060
15.
Review: Mechanisms of TIMP-3 accumulation and pathogenesis in Sorsby fundus dystrophy.
Mol Vis;
30: 74-91, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38601018
16.
Role of immune inflammation regulated by macrophage in the pathogenesis of age-related macular degeneration.
Exp Eye Res;
239: 109770, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38145794
17.
Optimizing the sodium iodate model: Effects of dose, gender, and age.
Exp Eye Res;
239: 109772, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38158173
18.
Conditional loss of Ube3d in the retinal pigment epithelium accelerates age-associated alterations in the retina of mice.
J Pathol;
261(4): 442-454, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37772657
19.
Preclinical evaluation of KH631, a novel rAAV8 gene therapy product for neovascular age-related macular degeneration.
Mol Ther;
31(11): 3308-3321, 2023 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37752703
20.
Comparative study of PRPH2 D2 loop mutants reveals divergent disease mechanism in rods and cones.
Cell Mol Life Sci;
80(8): 214, 2023 Jul 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-37466729